Question: The first Catholic church in the United States was founded where and when? Bonus: Who founded this church?
Answer: In the continental US, Old San Miguel Mission in Santa Fe was built somewhere between 1610 and 1628. It was founded by a group of Mexican Indians from Tlaxcala, Mexico, Franciscan friars and conquistadors.
If we include all US territories, the Cathedral of San Juan Batista in Puerto Rico was founded in 1521 by the bishop of San Juan, Alonso Manso.