Question: The earliest known permanent nativity scene was created for the first Rome Jubilee in 1300. Carved in marble by Arnolfi di Cambio in the late 13th century this nativity scene is kept in a niche that is the same dimensions as the cave where Jesus was born. Where in Rome would you find this presepe?
Answer: Saint Mary Major Basilica (Basilica di Santa Maria Maggiore)
Read more (and see pictures)
http://www.museoliberiano.net/en/museum--the-nativity-scene-by-arnolfo-di-cambio.html